Enrofloxacin - 25 grams
MOLECULAR FORMULA: C19H22FN3O3
MOLECULAR WEIGHT: 359.39
CAS Number: 93106-60-6
Appearance: Light yellow or yellow-orange powder
Solubility: Water: Slightly soluble
Melting Point: 221226°C
Storage Conditions: 28°C
Description: Enrofloxacin is a fluoroquinolone antibiotic commonly used in veterinary medicine.
Gentaur offers two forms of enrofloxacin, enrofloxacin (E016) and enrofloxacin
HCl (E007). Enrofloxcin is slightly soluble in aqueous solution and enrofloxacin
HCl is freely soluble at 10 mg/mL.
Mechanism of Action: Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. Because DNA gyrase is required
during DNA replication, subsequent DNA synthesis and ultimately cell division is inhibited.
Spectrum: Enrofloxacin is a broad spectrum antibiotic targeting a wide variety of gram
positive and gram negative bacteria and a few Mycoplasma species.
Microbiology Applications: Enrofloxacin is commonly used in clinical in vitro microbiological antimicrobial
susceptibility tests (panels, discs, and MIC strips) against gram positive, gram
negative, and certain Mycoplasma species. Medical microbiologists use AST
results to recommend antibiotic treatment options for infected patients.
Representative MIC values include:
Pseudomonas aeruginosa 0.5 µg/mL – 2 µg/mL
Escherichia coli 0.004 µg/mL – 0.03 µg/mL