Recombinant Human CD200 (C-6His) - 500 ug

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£ 1,143.25 1143.25 GBP £ 1,143.25

1,345.00 €

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    Accession Number: P41217

    Species: Human
    Expression System: Human 293 Cells
    Target Sequence: Gln31-Gly232
    Tag: C-6His
    Formulation: Lyophilized from a 0.2 um filtered solution of 2umM PB, 15umM NaCl, pH 7.4.

    Purity: >95% measured by SEC-HPLC


    Background:
    CD200, also known as OX-2 membrane glycoprotein, is a type I transmembrane protein that belongs to the immunoglobulin superfamily. CD200 is broadly but not ubiquitously expressed and is shown to be important for the regulation of the myeloid cell activity in various tissues. CD200 also acts as a costimulatory molecule for T-cell proliferation. Previous studies have found that CD200 plays an important role in the prevention of graft rejection, autoimmune diseases, and spontaneous abortion.

    Alternative Names: OX-2 Membrane Glycoprotein; MOX1; MOX2


    Citation: Yimin H., Edyta M. et al. Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model, Cell Reports 39(2), 2022